circad | circRNAs associated with diseases

hsa_circ_0045714
Gene	UNK	Organism	Human
Genome Locus	chr17:73808192-73809959:+	Build	hg19
Disease	Osteoarthritis (OA)	ICD-10	Polyarthrosis, unspecified (M15.9)
DBLink	Link to database	PMID	28795385
Experimental Method
Sample Type	OA Cartilage	Comparison	OA cartilage was isolated from the knee joints of 20 patients undergoing total knee arthroplasty (12 men and 8 women; age range 45-58 years), and normal articular cartilage was isolated from the knee joints of 10 trauma patients (4 men and 6 women; age range 33-56 years).
Method for Estimation	Quantitative PCR	PCR Details	Detailed Experimental Procedure
Primers (Experimented)	Forward CCGAGGTGCCCATTCCTG Reverse TTGGTGCAGTTGCCTTTCG	Statistics	Fold Change : Downregulated pvalue : p<0.05
Citation
Li, BF, Zhang, Y, Xiao, J, Wang, F, Li, M, Guo, XZ, Xie, HB, Xia, H, Chen, B (2017). Hsa_circ_0045714 regulates chondrocyte proliferation, apoptosis and extracellular matrix synthesis by promoting the expression of miR-193b target gene IGF1R. Hum. Cell, 30, 4:311-318.